Santos A., Pereira J. P., Pedroso de Lima M. C., Simões S. and Moreira J.N., In vitro modulation of Bcl-2 levels in small cell lung cancer cells: implications for therapeutic gene silencing. Submitted for publication, 2009.

 

J. N. Moreira, A. Santos, L. M. Bimbo, L. C. Gomes da Silva, M. C. Pedroso de Lima, S. Simões. Gene silencing therapy in small cell lung cancer – which agents, targets, and delivery systems? in Small Cell Carcinomas: Causes, Diagnosis, and Treatment, Nova Science, 2009. in press

Santos, A., Ribeiro, A.B., de Lima, M.C., Simoes, S. and Moreira, J.N., Simultaneous evaluation of viability and Bcl-2 in small-cell lung cancer. Cytometry A, 2008.

 

Moreira, J.N., Santos, A., Moura, V., Pedroso de Lima, M.C. and Simoes, S., Non-viral lipid-based nanoparticles for targeted cancer systemic gene silencing. J Nanosci Nanotechnol, 2008. 8(5): p. 2187-204.

 

Moreira, J.N., Santos, A. and Simoes, S., Bcl-2-targeted antisense therapy (Oblimersen sodium): towards clinical reality. Rev Recent Clin Trials, 2006. 1(3): p. 217-35.

 

Gaspar-Maia, A., Heidersbach, A., McManus, M., Meshorer, E., Ramalho-Santos, M. Chd1 regulates open chromatin and pluripotency of ES cells. Submitted

 

Wong, C.C., Gaspar-Maia, A., Ramalho-Santos, M., Reijo-Pera, R.A. 2008. High-efficiency stem cell fusion-mediated assay reveals Sall4 as an enhancer of reprogramming. PLoS One 3(4): e1955

 

Grskovic, M., Chaivorapol, C., Gaspar-Maia, A., Li, H., Ramalho-Santos, M. 2007. Systematic identification of cis regulatory sequences active in mouse and human embryonic stem cells. PLoS Genetics, 3(8): e145

 

Teles-Grilo, M.L., Duarte, S.M., Tato-Costa, J., Gaspar-Maia, A., Oliveira, C., Rocha, A.A., Marques, A., Cordeiro-da-Silva, A. , Azevedo, C.. 2007 Molecular karyotype analysis of Perkinsus atlanticus (Phylum Perkinsozoa) by pulsed field gel electrophoresis. Eur J Protistol. Nov;43(4):315-8.

 

Teles-Grilo, M.L., Tato-Costa, J., Duarte, S.M., Gaspar-Maia, A., Casal, G., Azevedo, C. 2007. Is there a plastid in Perkinsus atlanticus (Phylum Perkinsozoa)? Eur J Protistol. Jun;43(2):163-7.

 

Heidersbach, A., Gaspar-Maia, A., McManus, M., Ramalho-Santos, M. 2006. RNA interference in embryonic stem cells and the prospects for future therapies. Gene Therapy 13:478-86

 

Grandela C and Wolvetang E (2007) hESC Adaptation, Selection and Stability. Stem Cell Reviews. 2007. 3, 183-91.

 

Grandela C, Pera MF and Wolvetang EJ. p53 is required for etoposide-induced apoptosis of human embryonic stem cells. Stem Cell Research 2007. In Press

 

 

Sequeira-Mendes J, Díaz-Uriarte R, Apedaile A, Huntley D, Brockdorff N, and Gomez M (2009). Transcription Initiation Activity Sets Replication Origin Efficiency in Mammalian Cells. PLoS Genet 5(4): e1000446. doi:10.1371/journal.pgen.1000446 

 

Ferreira M, Fujiwara H, Morita K, Watt FM. An activating beta 1 integrin mutation increases conversion of benign to malignant skin tumours. Cancer Res 2009; 69(4): 1335-1342 .

 

Young ARJ, Narita M, Ferreira M, Kirschner K, Sadaie M, Darot JFJ, Tavaré S, Arakawa S, Shimizu S, Watt FM and Narita M. Genes Dev. 2009 Mar 11. [Epub ahead of print].

 

Santos SD, Carvalho AL, Caldeira MV and Duarte CB. Regulation of AMPAReceptors and synaptic plasticity. Neuroscience 2008 Feb 29 [Epub ahead of print].

 

Carvalho AL, Caldeira MV, Santos SD and Duarte CB. Role of the brain-derivedneurotrophic factor at glutamatergic synapses Br J Pharmacol. 2008 Mar;153 Suppl 1:S310-24.

 

Moreno AJ, Oliveira PJ, Nova CD, Alvaro AR, Moreira RA, Santos SM, Macedo, T. Unaltered hepatic oxidative phosphorylation and mitochondrial permeability transition in wistar rats treated with nimesulide: Relevance for nimesulide toxicity characterization. J Biochem Mol Toxicol. 2007;21(2):53-61.

 

Malva, J.O., Santos, S. & Macedo, T.R. (2004) Neuroprotective properties of Valeriana officinalis extracts. Neurotoxicity Research 6(2):131-40

 

Pereira, C.F., Santos, S.D., Ribeiro, C.F., Ali, S.F., and Macedo, T.R. (2004) A single exposure to morphine induces long-lasting hyporreactivity of rat caudate putamen dopaminergic nerve terminals. Ann. N.Y. Acad. Sci 1025:414-23

 

Nobrega-Pereira S and Marín O. Transcriptional control of neuronal migration and guidance decisions in the developing telencephalon. Submitted to Cerebral Cortex (Review).

 

Nobrega-Pereira S, Kessaris N, Du T, Kimura S, Anderson S, Marín O. Postmitotic Nkx2-1 controls the migration of telencephalic interneurons by direct repression of guidance receptors.

Neuron. 2008 Sep 11:59(5):733-45.

 

Lavreysen H, Wouters R, Bischoff F, Nobrega Pereira S, Langlois X, Blokland S, Somers M, Dillen L and Lesage ASJ. JNJ16259685, a highly potent, selective and systemically active mGlu1 receptor antagonist. Neuropharmacology. 2004 Dec: 47(7): 961-72.

 

Lavreysen H, Nobrega Pereira S, Leysen JE, Langlois X, Lesage ASJ. Metabotropic glutamate 1 receptor distribution and occupancy in the rat brain: a quantitative autoradiographic study using

[3H]R214127. Neuropharmacology. 2004 Apr: 46(5): 609-19.

Retinal Function in Best Macular Dystrophy: Relationship Between Electrophysiological, Psychophysical and Structural Measures of Damage. Invest Ophthalmol Vis Sci. 2008 Sep 4. [Epub ahead of print]

PMID: 18775865 [PubMed - as supplied by publisher]2: Related Articles, Links Maia-Lopes S, Castelo-Branco M, Silva E, Aguirre J, Riveiro-Alvarez R, Trujillo-Tiebas MJ, Ayuso C.

 

Gene symbol: BEST1. Disease: Best macular dystrophy. Hum Genet. 2008 Feb;123(1):112. No abstract available. PMID: 18386373 [PubMed - indexed for MEDLINE]3: Related Articles, Links Maia-Lopes S, Castelo-Branco M, Silva E, Aguirre J, Riveiro-Alvarez R, Trujillo-Tiebas MJ, Ayuso C.

 

Gene symbol: ABCA4. Disease: Macular dystrophy. Hum Genet. 2008 Feb;123(1):112. No abstract available. PMID: 18386369 [PubMed - indexed for MEDLINE]4: Related Articles, Links Maia-Lopes S, Castelo-Branco M, Silva E, Aguirre J, Riveiro-Alvarez R, Trujillo-Tiebas MJ, Ayuso C.

 

Gene symbol: ABCA4. Disease: Macular dystrophy. Hum Genet. 2008 Feb;123(1):111. No abstract available. PMID: 18386365 [PubMed - indexed for MEDLINE]5: Related Articles, Links Maia-Lopes S, Castelo-Branco M, Silva E, Villaverde C, Aguirre J, Trujillo-Tiebas MJ, Ayuso C.

 

Gene symbol: BEST1. Disease: Best macular dystrophy. Hum Genet. 2008 Feb;123(1):111. No abstract available. PMID: 18386364 [PubMed - indexed for MEDLINE]6: Related Articles, Links Maia-Lopes S, Castelo-Branco M, Silva E, Villaverde C, Aguirre J, Trujillo-Tiebas MJ, Ayuso C.

 

Gene symbol: BEST1. Disease: Best macular dystrophy. Hum Genet. 2008 Feb;123(1):111. No abstract available. PMID: 18386360 [PubMed - indexed for MEDLINE]7: Related Articles, LinksMaia-Lopes S, Castelo-Branco M, Silva E, Villaverde C, Aguirre J, Trujillo-Tiebas MJ, Ayuso C.

 

Gene symbol: BEST1. Disease: Best macular dystrophy. Hum Genet. 2008 Feb;123(1):110-1. No abstract available. PMID: 18386356 [PubMed - indexed for MEDLINE]8: Related Articles, Links Maia-Lopes S, Castelo-Branco M, Silva E, Villaverde C, Aguirre J, Trujillo-Tiebas MJ, Ayuso C.

 

Gene symbol: BEST1. Disease: Best macular dystrophy. Hum Genet. 2008 Feb;123(1):110. No abstract available. PMID: 18386355 [PubMed - indexed for MEDLINE]9: Related Articles, Links Maia-Lopes S, Castelo-Branco M, Silva E, Villaverde C, Aguirre J, Trujillo-Tiebas MJ, Ayuso C.

 

Gene symbol: BEST1. Disease: Best macular dystrophy. Hum Genet. 2008 Feb;123(1):110. No abstract available. PMID: 18386350 [PubMed - indexed for MEDLINE]10: Related Articles, Links Maia-Lopes S, Silva ED, Silva MF, Reis A, Faria P, Castelo-Branco M.

 

Evidence of widespread retinal dysfunction in patients with stargardt disease and morphologically unaffected carrier relatives. Invest Ophthalmol Vis Sci. 2008 Mar;49(3):1191-9. PMID: 18326749 [PubMed - indexed for MEDLINE]11: Related Articles, LinksSilva MF, Maia-Lopes S, Mateus C, Guerreiro M, Sampaio J, Faria P, Castelo-Branco M. Retinal and cortical patterns of spatial anisotropy in contrast sensitivity tasks. Vision Res. 2008 Jan; 48(1):127-35. Epub 2007 Dec 11. PMID: 18067943 [PubMed - indexed for MEDLINE]

Ana Luísa Vital, Maria Dolores Tabernero, Abel Castrillo, Olinda Rebelo, Hermínio Tão, Fernando Gomes, Ana Belen Nieto, Maria Celeste Lopes, Alberto Orfao*; GENE EXPRESSION PROFILES OF HUMAN GLIOBLASTOMAS ARE ASSOCIATED WITH BOTH TUMOR CYTOGENETICS AND HISTOPATHOLOGY; Neuro-Oncoogy, May 18, 2010. [Epub ahead of print]

Vital AL, Tabernero MD, Crespo I, Rebelo O, Tão H, Gomes F, Lopes MC, Orfao A. Intratumoral patterns of clonal evolution in gliomas. Neurogenetics,11(2): 227-39, 2010