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Metabolism and Disease: Causes and Consequences of Non-Alcoholic Fatty Liver Disease (NAFLD)
March 6 - 10
Metabolism and Disease: Causes and Consequences of Non-Alcoholic Fatty Liver Disease (NAFLD)

PDBEB 2016/2017 Edition

Organized by the Metabolism, Aging and Disease Area of the CNC
(Paulo Oliveira, John Jones, João Ramalho Santos)

Monday, March 6
9:30 – 10:30: John Jones (CNC) What is metabolism?
10:30 – 11:30: Carlos Palmeira (CNC) Mitochondrial function in the context of liver diseases
11:30 – 13:00: Fernanda Borges (FCUP) Bridging the gap between Nature and antioxidant setbacks: a drug discovery trail for liver diseases
14:30 – 16:00: Rogério Ribeiro (APDP, UA) NAFLD: definition and progression. Nutrition and physical activity as interventions
16:00 – 16:30: José Teixeira (CNC) Mitochondrionotropic derivatives of natural antioxidants and NAFLD: the MitoBOOST project
16:30 - Interaction time

Tuesday, March 7

10:00 – 11:00: John Jones (CNC) Measuring liver metabolism in health and disease
11:00 – 12:30: Paula Macedo (APDP, CEDOC): NAFLD in the context of obesity and insulin resistance
14:00 – 15:00: Paulo J. Oliveira (CNC) Drug-induced mitochondrial toxicity and fatty liver
15:00 – 16:00: Henrique Alexandrino (FMUC e CHUC) Hepatic ischemia and reperfusion: how to preserve hepatocyte viability
16:00 - Interaction time

Wednesday, March 8

10:00 – 11:00: Paulo J. Oliveira (CNC) An overview of the FOIE GRAS project
11:00 – 11:30: Susana Pereira (CNC) Priming liver metabolism in utero: consequences for chronic diseases in the adulthood
14:00 – 15:00: Miguel Castelo-Branco (ICNAS/IBILI) Basic principles of in vivo studies of metabolism using imaging
15:00 – 16:00: Miguel Castelo-Branco (ICNAS/IBILI) Multimodal and multiorgan studies in metabolic disorders: brain, heart and liver
16:00 - Interaction time

Thursday, March 9
10:00 – 11:00: Vilma Sardão (CNC) Osteoporosis, menopause and NAFLD
11:00 – 12:30: Cecília Rodrigues (iMed.ULisboa, FF, ULisboa) Necroptosis and miRNA in liver diseases
14:00 – 15:30: José Magalhães (FDEUP) Physical activity in NAFLD rodent models: a tale of mitochondria, quality control and endoplasmic reticulum
15:30 – Interaction time

Friday, March 10
10:00 – 13:00: Work presentations by students

Evaluation of the course:

Students will be paired in groups of two and asked to present a 10 minutes pitch on a hypothetical business idea related to NAFLD management, diagnosis (including medical devices or biomarkers), prevention or treatment. Imagination is valued, as opposed to ideas that already exist. Powerpoint slides can be used (or without any support), and the time allocated for each group will be strictly enforced. After the pitch, the other students and the instructors will ask questions.

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