Home
About BEB
Curriculum
Admission
CNC Research
BEB in the Media
 
 
Drug Development (MIT-Portugal)
 
February 1 - 12
Joao Nuno Moreira
MIT-PT PROGRAMME 2009/2010
PRINCIPLES AND PRACTICE IN DRUG DEVELOPMENT 
ELECTIVE COURSE
Center for Neuroscience and Cell Biology - University of Coimbra
February 1-12, 2010
CNC Auditorium, 2nd floor
João Nuno Moreira, Luís Pereira de Almeida, Sérgio Simões, Conceição P. Lima, Stan Finkelstein


February 1
 
09.00 h - Introduction to the course
Conceição Pedroso de Lima  PhD (CNC)
Sérgio Simões  PhD (CNC)
João Nuno Moreira  PhD (CNC)
Luís Pereira de Almeida  PhD (CNC)
 
10.00 h - The Pharmaceutical Industry and the Drug Development Process
Stan N. Finkelstein  MD, PhD (Senior Research Assistant in the MIT Engineering Systems Division and Associate Professor of Medicine at Harvard Medical School)
 
 
16.00 h - Basic Science I – Discovery Innovation and Emerging Technologies; Basic Business
Anthony J. Sinskey  PhD (Professor of Biology at MIT)
 
 
February 2
 
10.00 h - Drugable biological targets and concept design
Patrício Soares da Silva  MD, PhD (BIAL, Indústria Farmacêutica, Portugal)
 
11.00 h - Clinical development of CNS active drugs
Teresa Nunes  MD (BIAL, Indústria Farmacêutica, Portugal)
 
14.00 h - Pharmacology and toxicology of new chemical entities
Lyndon C. Wright  PhD (BIAL, Indústria Farmacêutica, Portugal)
 
15.00 h - Development of new chemical entities: from bench to industrial production
David A. Learmonth PhD (BIAL, Indústria Farmacêutica, Portugal)
 
 
February 3
 
10.00 h - Regulatory Affairs – the perspective from EMEA
Rogério Gaspar  PhD (Faculty of Pharmacy, University of Lisbon, Portugal)
 
15.00 h - Drug development and the supply chain for drugs in developing countries
Prashant Yadav  PhD (Professor at the Zaragoza Logistics Center in Spain)
 
 
 
February 4
 
9.00 h - FDA Process, Off-Label Prescribing, Insurance Coverage
Stan N. Finkelstein  MD, PhD (Senior Research Assistant in the MIT Engineering Systems Division and the Harvard-MIT Division of Health Sciences and Technology)
 
16.00 h - Technology transfer – the perspective from MIT
Lauren Foster (MIT, USA)
 
 
February 5
 
10.00 h - Some issues in drug development: discussion of case studies
Miguel Prazeres  PhD (Instituto Superior Técnico, Technical University of Lisbon)
 
14.00 h - Visit to Bluepharma, Pharmaceutical Industry SA
 
 
February 8
 
10 h - Alfama – the entrepreneurial side of drug development
Nuno Arantes-Oliveira  PhD (President and CEO of Alfama)
 
16 h -Biotech Cluster Study and Related Issues
Thomas J. Allen  PhD (Howard Johnson Professor Emeritus of Management at MIT)
 
 
February 9
 
09.00 h - Nanotechnology for drug and gene targeting
Conceição Pedroso de Lima  PhD (CNC, Portugal)
Sérgio Simões  PhD (CNC, Portugal)
João Nuno Moreira  PhD (CNC, Portugal)
Luís Pereira Almeida  PhD (CNC, Portugal)
 
10.00 h - Nanotechnology for drug and gene targeting(cont.)
 
14.30 h - Visit to Biocant Park – Innovation Center in Biotechnology
 
 
February 10
 
10.00 h - Biotecnol and the Business of Biopharmaceuticals
Philip Cunnah  PhD (Director of Process Development and Manufacturing, Biotecnol SA)
 
16.00 h - Economic evaluation of pharmaceuticals
Terrence Norchi  PhD (CEO of Arch Therapeutics)
 
 
February 11
 
09.00 h - Manufacturing I
G. K. Raju  PhD (Research Associate at MIT)
 
15.30 h - Manufacturing II
G. K. Raju  PhD (Research Associate at MIT)
 
17.30 h - Manufacturing III
Charles L. Cooney  PhD (Robert T. Haslam Professor of Chemical Engineering at MIT)
 
This session will also count with the participation of Guy Villax, CEO from Hovione.
 
February 12
 
Student s presentations

Readings
 
CO Rev Ryter Otterbein 2004.pdf
Drews-Magic bullets.pdf
Motterlini review ExpOp 2005.pdf
Soares EAE JCI 2007.pdf

JNN08.pdf

Feb-10-Leiden-Canaries.pdf

Feb-11-Schiff-Biotechnology.pdf

Feb-12-Kishimoto-Contaminated.pdf

Feb-12-Laurencin-The-FDA.pdf

Feb-12-Schwartz-Heparin.pdf

Feb-1-Finkelstein-Pharma-Industry-Today.pdf

Feb-1-Posner-First-Admin-Guide-2000.pdf

Feb-2-Rang-Chapter-1-Development.pdf

Feb-2-Rang-Chapter-2-Nature-Disease.pdf

Feb-2-Rang-Chapter-3-Therapeutic-Modal.pdf

Feb-3-Livingston-Toward-Mechanism.pdf

Feb-3-Walsh-Chapter1-Pharmaceuticals.pdf

Feb-3-Walsh-Chapter2-Drug-Develop.pdf

Feb-4-Zivin-Understanding.pdf

Feb-5-Radley-Off-Label.pdf

Feb-8-Edwards-Value-Creation.pdf

February-2008-MIT-Principles-Readings.pdf

Introduction_MIT BEB 09_10.pdf

Yadav-MIT Portugal 2010.pdf

2010_02_03_MITCNC_RSG.rar

Finkelstein-Reason-Rx-Feb-2010.pdf

Finkelstein-Drug-Reg-Feb-2010.pdf

Finkelstein-Brief-Econ-Feb-2010.pdf

Alfama Coimbra 08Feb10.pdf

Lauren Foster_MIT-Portugal Feb 4 10.pdf

Rogue APIs  A Ticking Time Bomb - Summary of GVs presentation at the AAPS annual convention 2009.pdf

back
 
© 2017 BEB - Doctoral Programme in Experimental Biology and Biomedicine powered by ponto.C