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Molecular Biotechnology
 
October 12 - 23
Paula Veríssimo, Sandra Ribeiro Sukalyan Chaterjee

paulav@ibili.uc.pt
Molecular Biotechnology
From protein to gene, from gene to protein

Paula Veríssimo
Sandra Ribeiro
Sukalyan Chaterjee
Rui Cruz
Raquel Vinhas
 
Lab. Biotecnologia Molecular do CNC
Dep. Bioquímica, Universidade de Coimbra
IBMC
IBMC
The Course Schedule is available at the Public Information (below)
Lecture
9:00 h - CNC Auditorium, 2nd floor
 
  • Lect.1 Cloning strategies
  • Lect.2 Expression of cloned genes in prokaryotes
  • Lect. 3& 4: Expression of cloned genes in eukaryotes  
  • Lect. 5:Recombinant protein production
  • Lect. 6:Protein purification
  • Lect. 7: Protein engineering
  • Lect. 8: Protein structure: historical perspective
  • Lect 9: Methods for the determination of protein 3D structures
  • Lect 10: Protein folding and unfolding: misfolding disorders
 
 
 
Practical course 
 ·         Protein engineering
·         Expression, purification and characterisation of recombinant enzymes
·         Structural analysis of biomedically-relevant enzymes; mechanism of action of
compounds targeting blood clotting, HIV infection and hypercholesterolemia.
 
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