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Cell Biology
 
October 6 - 9
Edgar Gomes

er.gomes@gmail.com
MOLECULAR CELL BIOLOGY
 
 
6-9 October
 
Coordinators: Edgar R. Gomes (UPMC, Paris, France), Carlos B. Duarte (U. Coimbra, Portugal)
 
Lecturers:

 

Phong Tran
U. of Pennsylvania, Philadelphia USA &
Institut Curie, Paris
France
 
Alexander Palazzo
Dept. of Biochemistry
U. Toronto
Canada
 
Edgar R. Gomes
U. Pierre et Marie Curie, Paris
France
Helder Maiato
IBMC, U. do Porto, Porto
Portugal

 

 
 
Tuesday, October 6
9:30 - Introduction
10:00 – A tale of three filaments I (Edgar)
11:00 - A tale of three filaments II (Edgar)
11:45 – Lunch break
 
13:45 - Imaging in Cell Biology (part I) (Phong)
14:45 – Break
15:15 – Imaging in Cell Biology (part II) (Phong)
16:30 – End
 
Wednesday, October 7
9:00 – Controlling the cytoskeleton (Edgar)
10:00 – Break
10:15 - paper 1: (Selected by Phong)
11:15paper 2: (Selected by Phong)
12:00 – Lunch Break
 
14:00 – Mitosis ( Helder)
15:15 - Paper 3: (selected by Helder)
16:30 - Paper 4: (selected by Edgar)
17:45 - End
 
Thursday, October 8
9:00 – Cell Polarity and the Localization of Ribonucleoprotein Complexes (Alex)
10:15 – Break
10:30 – Assembling the Ribonucleoprotein Complex (Alex)
11:45 – Lunch Break
 
14:00 – Paper 5: (selected by Alex)
15:15 - Paper 6: (selected by Alex)
16:30 - End
20:00 – “official” course dinner.
 
 
Friday, October 9
11:00 – Paper 7: (selected by Edgar)
 
12:30 – Lunch Break
16:00 – Seminar – “Specialized Nuclear Export of mRNA Encoding Secretory and Mitochondrial Proteins” Alexander Palazzo
 
 
 
Papers for the journal club:
 
Paper1:
Fu, C., Ward, J. J., Loiodice, I., Velve-Casquillas, G., Nedelec, F. J., and Tran, P. T. (2009). Phospho-Regulated Interaction between Kinesin-6 Klp9p and Microtubule Bundler Ase1p Promotes Spindle Elongation. Developmental Cell 17, 257-267.
 
Paper2:
Khmelinskii, A., Roostalu, J., Roque, H., Antony, C., and Schiebel, E. (2009). Phosphorylation-Dependent Protein Interactions at the Spindle Midzone Mediate Cell Cycle Regulation of Spindle Elongation. Developmental Cell 17, 244-256.
 
Paper3:
Liu, D., Vader, G., Vromans, M. J. M., Lampson, M. A., and Lens, S. M. A. (2009). Sensing Chromosome Bi-Orientation by Spatial Separation of Aurora B Kinase from Kinetochore Substrates. Science 323, 1350-1353.
 
Paper4:
Campellone, K. G., Webb, N. J., Znameroski, E. A., and Welch, M. D. (2008). WHAMM Is an Arp2/3 Complex Activator That Binds Microtubules and Functions in ER to Golgi Transport. Cell 134, 148-161.
 
Paper 5:
Splicing of oskar RNA in the nucleus is coupled to its cytoplasmic localization. Hachet O, Ephrussi A. Nature. 2004 Apr 29;428 (6986):959-63.
 
Paper 6:
The signal sequence coding region promotes nuclear export of mRNA. Palazzo AF, Springer M, Shibata Y, Lee CS, Dias AP, Rapoport TA. PLoS Biol. 2007 Dec;5(12):e322.
 
Paper7:
Gomes, E. R., Jani, S., and Gundersen, G. G. (2005). Nuclear Movement Regulated by Cdc42, MRCK, Myosin, and Actin Flow Establishes MTOC Polarization in Migrating Cells. Cell 121, 451-463.
 
 

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