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Biomedical Magnetic Resonance: Molecular Imaging and Metabolism
 
March 1 - 4
Coordinator: Carlos Geraldes

Lecturers
Carlos F. Geraldes, Ph.D.
Department of Biochemistry, FCT, University of Coimbra
Sebastián Cerdán, Ph.D.
Instituto de Investigaciones Biomédicas “Alberto Sols”, CSIC/Univ. Autonoma de Madrid, Madrid, Spain
Craig R. Malloy, M.D.
University of Texas Southwestern Medical Center at Dallas and Dallas VA Medical Center, Dallas, Texas, USA
Silvio Aime, Ph.D.
Chemistry Department and Center for Molecular Imaging, University of Torino, Torino, Italy
Course Schedule
Tuesday 1 March: Introduction and Background
9-10h
Introduction to Biomedical NMR Spectroscopy
 
Carlos F. Geraldes
10.30-11.30h
Basic NMR Parameters and Their Biomedical Information Content
 
Carlos F. Geraldes
14-15h
Introduction to Magnetic Resonance Imaging (MRI)
 
Carlos F. Geraldes
Wednesday 2 March: 13C and 2H NMR of Brain Metabolism: cells and in vivo studies
9-10h
Cellular and subcellular metabolism of water as detected by multinuclear NMR spectroscopy
 
Sebastián Cerdán
12-13h
Energetics of glutamatergic and gabaergic neurotransmissions in the adult mammalian brain
 
Sebastián Cerdán
14.30-17.30h
Analysis and discussion of papers
 
 
Ana Filipa Simões
 
 
Susana Isabel Silva
 
 
Luís Paulo Valente
Thursday 3 March: 13C and 2H NMR of Heart and Liver Metabolism
9-10h
Substrate Oxidation in the Heart by 13C NMR
 
Craig Malloy
10.30-11.30h
2 H and 13C NMR for Liver Metabolism and Clinical Applications
 
Craig Malloy
14-17h
Analysis and discussion of papers
 
 
 
Ana Margarida Sousa and Bruno Miguel Gago
 
 
Carla Alexandra Bento and João Henrique Duarte
 
 
Rita Mafalda Rocha
Friday 4 March: Molecular Imaging by NMR
9-10h
Basics of MRI Contrast Agents
 
Silvio Aime
10.30-11.30h
Responsive and Targeting MRI Contrast Agents
 
Silvio Aime
Seminars:
 
15.00 h
Fluxes in Metabolic Networks of the Liver by NMR
 
Craig R. Malloy
16.00 h
Magnetic Resonance Contrast Agents for Molecular Imaging Applications
 
Silvio Aime

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