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Neurosystems
 
January 9 - 13
Coordinator: Miguel Castelo-Branco

Main goals of the course
To study the relevance of in vivo models (animal and human) to understand neuronal function in health and disease. Sensory and motor systems will be emphasized since they are better suited to be explored using quantitative approaches.
COURSE SCHEDULE
Day 1
9th January
9.15 am
Introductory notes
 
Miguel Castelo-Branco
9.30 – 10.45 am
Lecture 1 - Basic principles of organization of the visual system. From the retina to the cortex
 
Miguel Castelo-Branco
11.00 – 11.50
Lecture 2 - Structure-Function relationships in the visual system. Implications for genotype-phenotype relationships in retinal and cortical disorders
 
Miguel Castelo-Branco
 
 
14h 30m
Challenges in choosing a lab and a PhD project within the scope of a Doctoral Program.
 
Discussion with Faculty members (M. Castelo-Branco, R. Costa & E. Formisano).
 
Paper and group assignments for discussion
 
Day 2
10th January
9.15 am – 10h 15
Lecture 1 - Visual cortical maps. Development and plasticity.
 
Louis Toth
10.30 am – 11h 50
Lecture 2 - Principles of Functional Brain Imaging
 
Elia Formisano
 
 
15.00 h
Paper presentations and discussion (References from M. Castelo-Branco and from L.Toth).
 
Day 3
11th January
9.15 am – 10h 45m
Lecture 1 - Looking at brain function with multiple temporal and spatial scales: From single cell neurophysiology to brain imaging.
 
Louis Toth
 
 
14h30 – 16h00
Lecture 2 - Principles of organization of the auditory system in animals and humans
 
Elia Formisano
16h15m
Paper Presentation. References form L. Toth (1).
 
Day 4
12th January
9h 15m – 10h 15m
Lecture 1 - Neural mechanisms underlying learning and memory.
 
Rui Costa
10h 45m – 11h 45m
Lecture 2 - Studying actions and skills in animal models.
 
Rui Costa
 
 
14h30 – 17h30
Paper presentations and discussion (References from E.Formisano).
 
13th January
9h30 – 12h00
Paper presentations and discussion (References from R. Costa).
 
 
16h00
Seminar: Pharmacogenetic approaches to study cognitive and sensorimotor dysfunction
 
Rui Costa
 
Dept. of Neurobiology, Duke University Medical Center
 
Readings
 
Reference List from M. Castelo-Branco
General Reviews
 
 
 
 
2 papers for discussion (Miguel Castelo-Branco).
 
 
 
3 Review papers  (Louis Toth):
 
 
 
Papers for discussion (L. Toth):
 
 
 
 
General Reviews (Elia Formisano)
 
 
 
 
 
 
3 papers for discussion (E. Formisano)
 
 
 
 
General Reviews (Rui Costa):
 
 
Additional:
 
 
 
3 papers for discussion (R. Costa)
 
 
 
Affiliation and contacts
Miguel Castelo-Branco - IBILI Faculdade de Medicina – Az. de Sta Comba, Celas 3000-354 Coimbra
tel  239 480286 ou 239 480220; telem 936360050; fax 239 480280
5 selected publications
 
 
 
 
 
 
Louis Toth, PhD - Assistant Professor, Boston University School of Medicine, 715 Albany Street, L – 1004, Boston, MA 02118; Phone: 617-638-5885; Fax: 617-638-4355
5 selected publications
 
Toth LJ, Kim DS, Rao SC, Sur M (1997)  Integration of local inputs in visual cortex.  Cer. Ctx.  7:703-710.
 
Toth LJ, Assad JA (2002)  Dynamic coding of behaviorally relevant stimuli in parietal cortex   Nature 415:165-8.
 
Van Hooser SD, Heimel JAF, Chung S, Nelson SB, Toth LJ (2005) Orientation selectivity without orientation maps in visual cortex of a highly visual mammal J. Neurosci. 25:19-28.
 
 
Dr. Elia Formisano, Assistant Professor - Dep. Of Cognitive Neuroscience, Univ. of Maastricht, The Netherlands
Room 4.738; Tel: +31 43 3884040
5 selected publications
 
 
 
 
 
Rui M. Costa - Dept. of Neurobiology, Duke University Medical Center, Bryan Research Building, Research Drive, Room 333, Box 3209, Durham NC 27710, USA
Tel: (919)668-3171 or (919) 668-6107; Fax: (919) 684-5435; webpage: www.duke.edu/~costa
5 selected publications
 
 
 
 

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