Coordinators: Anália do Carmo (CNC), Maria Celeste Lopes, (CNC), Sukalyan Chaterjee (CNC)
Place: CNC Seminar Room/Anfiteatro de Farmacologia (Faculdade de Medicina da Universidade de Coimbra- Pólo I, 1º Andar)
Lecturers: Vivek Mittal, Ph.D Assistant Professor Cold Spring Harbor Laboratory New York, USA Website: http://www.cshl.edu/public/SCIENCE/mittal.html Alea Mills, Ph.D Associate Professor Cold Spring Harbor Laboratory New York, USA Website: http://www.cshl.edu/public/SCIENCE/mills.html Fernando Schmitt Ph.D Associate Professor Medicine Faculty of the Porto University IPATIMUP Porto, Portugal Iris Caramalho, Ph.D Gulbenkian Institute Oeiras, Portugal João Barata Ph.D Cancer Biology Unit Institute of Molecular Medicine Lisboa, Portugal Website: http://www.imm.ul.pt/indexi.html João Nuno Moreira, Ph, D Faculty Pharmacy of Coimbra Coimbra University Coimbra, Portugal
COURSE SCHEDULE
Monday (March 10th)
9:30-10:30 – Introduction: Instructors and Course participants .
Vivek Mittal
10:30-11:30 – Brief historical perspective and hallmarks of cancer.
Alea Mills
11:30-12:00 – Break
12:00-13:00 - Signal transduction aberrations in cancer
João Barata
13:00- 14:30 – Lunch
14:30-15:30– "Novel" concepts in cancer signal transduction
João Barata
15:30-15:45 – Break
15:45-16:45 - Journal Club – Group 1
Coordinator: João Barata
16:45-17:45 - Journal Club – Group 2
Coordinator: João Barata
Tuesday (March 11th)
9:00-10:00 – Tumor microenvironment in cancer progression
Vivek Mittal
10:00-10:15 – Break
10:15 – 11:00 – Tumor microenvironment in metastasis initiation and progression
Vivek Mittal
11:00-11:30 – Break
11:30-12:30 – Genome wide technologies in cancer research
Vivek Mittal
13:00-14:30 – Lunch
14:30-15:30– Journal Club – Group 3
Coordinators:Vivek Mittal, Alea Mills
Wednesday (March 12th)
9:00-10:00 – Câncer gene discovery: a chromosome engineering approach
Alea Mills
10:00-10:15 – Break
10:15 – 11:00 – The tumor suppressive mechanism of cellular senescence
Alea Mills
11:00-11:30 – Break
11:30-12:30 – Epigenetics & Cancer
Alea Mills
13:00-14:30 – Lunch
14:30-15:30– Journal Club – Group 4
Coordinators: Alea Mills, Vivek Mittal
15:30-16:00–Break
16:00-17:00 – Seminar: "Bone marrow-derived stem/progenitor cells control primary tumor growth, and initiation and progression of metastasis."
Vivek Mittal
20:00 – “Official” course dinner.
Thursday (March 13th)
9:00-10:00 – Tumors of the immune system
Iris Caramalho
10:00-10:15 – Break
10:15 – 11:00 – Immune response to tumors
Iris Caramalho
11:00-11:30 – Break
11:30-12:30 – Evasion of immune responses by tumors
Iris Caramalho
13:00-14:30 – Lunch
14:30-15:30– Journal Club – Group 5
Coordinators: Iris Caramalho, Alea Mills, Vivek Mittal
Friday (March, 14th)
9:00-10:00 – Targeting nanopharmaceuticals: impact on cancer therapy
João Nuno Moreira
10:00-10:15 – Break
10:15 – 11:15 – Journal Club – Group 6
Coordinator: João Nuno Moreira
11:15-14:30 – Lunch
14:30-15:15– Role of EGFR and HER2 in breast cancer
Fernando Schmitt
15:45-16: 45– Journal Club – Group 7
Coordinator: Fernando Schmitt
Students Evaluation
Each group is assigned one paper, which will represent the pivotal work of students PhD (just concluded), i.e., the students will assume that this is “their” work, which they have just published. Each group will first introduce the general points of the work to her/his classmates, then orally discuss what they would do next in terms of career development. In other words: which experiments would be important to do next and which directions the project would take (or should not take). Course organizers suggest that students read a review on the oncobiology basis Hanahan_2000_ artigo de revisão para todos os grupos.pdf
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