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Oncobiology
 
March 10 - 14
Anália do Carmo, Maria Celeste Lopes, Sukalyan Chaterjee
Coordinators: Anália do Carmo (CNC), Maria Celeste Lopes, (CNC), Sukalyan Chaterjee (CNC)
Place: CNC Seminar Room/Anfiteatro de Farmacologia (Faculdade de Medicina da Universidade de Coimbra- Pólo I, 1º Andar)


Lecturers:
Vivek Mittal, Ph.D
Assistant Professor
Cold Spring Harbor Laboratory
New York, USA
Website: http://www.cshl.edu/public/SCIENCE/mittal.html

Alea Mills, Ph.D
Associate Professor
Cold Spring Harbor Laboratory
New York, USA
Website: http://www.cshl.edu/public/SCIENCE/mills.html

Fernando Schmitt Ph.D
Associate Professor
Medicine Faculty of the Porto University
IPATIMUP
Porto, Portugal

Iris Caramalho, Ph.D
Gulbenkian Institute
Oeiras, Portugal

João Barata Ph.D
Cancer Biology Unit
Institute of Molecular Medicine
Lisboa, Portugal
Website: http://www.imm.ul.pt/indexi.html

João Nuno Moreira, Ph, D
Faculty Pharmacy of Coimbra
Coimbra University
Coimbra, Portugal
 

COURSE SCHEDULE

Monday (March 10th)
9:30-10:30 – Introduction: Instructors and Course participants .
Vivek Mittal

10:30-11:30 – Brief historical perspective and hallmarks of cancer.
Alea Mills

11:30-12:00 – Break

12:00-13:00 - Signal transduction aberrations in cancer
João Barata

13:00- 14:30 – Lunch

14:30-15:30– "Novel" concepts in cancer signal transduction
João Barata

15:30-15:45 – Break

15:45-16:45 - Journal Club – Group 1
Coordinator: João Barata

16:45-17:45 - Journal Club – Group 2
Coordinator: João Barata

Tuesday (March 11th)
9:00-10:00 – Tumor microenvironment in cancer progression
Vivek Mittal

10:00-10:15 – Break

10:15 – 11:00 – Tumor microenvironment in metastasis initiation and progression
Vivek Mittal

11:00-11:30 – Break

11:30-12:30 – Genome wide technologies in cancer research
Vivek Mittal

13:00-14:30 – Lunch

14:30-15:30– Journal Club – Group 3
Coordinators:Vivek Mittal, Alea Mills

Wednesday (March 12th)
9:00-10:00 – Câncer gene discovery: a chromosome engineering approach
Alea Mills

10:00-10:15 – Break

10:15 – 11:00 – The tumor suppressive mechanism of cellular senescence
Alea Mills

11:00-11:30 – Break

11:30-12:30 – Epigenetics & Cancer
Alea Mills

13:00-14:30 – Lunch

14:30-15:30– Journal Club – Group 4
Coordinators: Alea Mills, Vivek Mittal

15:30-16:00–Break

16:00-17:00 – Seminar: "Bone marrow-derived stem/progenitor cells control primary tumor growth, and initiation and progression of metastasis."
Vivek Mittal

20:00 – “Official” course dinner.

Thursday (March 13th)
9:00-10:00 – Tumors of the immune system
Iris Caramalho

10:00-10:15 – Break

10:15 – 11:00 – Immune response to tumors
Iris Caramalho

11:00-11:30 – Break

11:30-12:30 – Evasion of immune responses by tumors
Iris Caramalho

13:00-14:30 – Lunch

14:30-15:30– Journal Club  – Group 5
Coordinators: Iris Caramalho, Alea Mills, Vivek Mittal

Friday (March, 14th)
9:00-10:00 – Targeting nanopharmaceuticals: impact on cancer therapy
João Nuno Moreira

10:00-10:15 – Break

10:15 – 11:15 – Journal Club – Group 6
Coordinator: João Nuno Moreira

11:15-14:30 – Lunch

14:30-15:15– Role of EGFR and HER2 in breast cancer
Fernando Schmitt

15:45-16: 45– Journal Club  – Group 7
Coordinator: Fernando Schmitt
 
Students Evaluation
Each group  is assigned one paper, which will represent the pivotal work of students PhD (just concluded), i.e., the students will assume that this is “their” work, which they have just published. Each group will first introduce the general points of the work to her/his classmates, then orally discuss what they would do next in terms of career development. In other words: which experiments would be important to do next and which directions the project would take (or should not take).
Course organizers suggest that students read a review on the oncobiology basis Hanahan_2000_ artigo de revisão para todos os grupos.pdf
 
 
 
 
 
 
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