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Cell Biology of Infection
December 3 - 5
Otília Vieira
Coordinator: Otilia Vieira (vieira@cnc.cj.uc.pt)
Prof. Dr. Gerrit van Meer - Membrane Enzymology Bijvoet Center/Institute of Biomembranes Utrecht University, The Netherlands
Prof. Dr. Winchil Vaz - Department of Chemistry, University of Coimbra, 3004-535 Coimbra, Portugal
Marta Miaczynska, PhD - International Institute of Molecular and Cell Biology (IIMCB) Warsaw, Poland and Max-Planck Institute for Molecular Cell Biology and Genetics, Dresden, Germany
Otilia V. Vieira, PhD - Center for Neurosciences and Cell Biology, University of Coimbra, Portugal
Carla M. Cardoso - Center for Neurosciences and Cell Biology, University of Coimbra, Portugal
Luisa Jordao - Faculty of Pharmacy, University of Lisbon, Portugal.
Why an advanced course on Cell Biology of Infection?
The treatment and prevention of infection is becoming a big challenge since more and more pathogens are becoming resistant to multiple drugs and effective vaccines do not exist for the majority of them. These limitations argue strongly for a better understanding of the mechanistic basis of infection in terms of the molecular and cellular mechanisms that regulate host-pathogen interactions. Such an understanding may eventually lead to better weapons for preventing and combating infectious processes that will ultimately benefit us all.
This course will have lectures and scientific discussions based on recent papers published in the area of infection and chosen by the senior scientists involved in this course.
In this second part the PhD students will have an active participation.

Wednesday, December 3
9h30 – 10h00: Introduction to the course (O. Vieira)
10h00 -12h00: From model to Cellular Membranes (W. Vaz)
15h00 - 16h15: Lipid organization and dynamics in animal cells (G. van Meer)
16h30 – 17h45: Mechanisms of entry into cells: pathways and regulators of endocytosis (M. Miaczynska)
Thursday, December 4
9h30 - 10h45: How viruses and toxins abuse of cellular lipids (G. van Meer)
11h00 - 12h15: Signaling from endosomal compartments in cell physiology and in infection (M. Miaczynska)
15h00 - 16h15: Host-pathogen interactions and manipulation of the cellular trafficking pathways (C. Cardoso)
16h30 - 17h45: Mycobacterium spp interaction with macrophages (L. Jordao)
Friday, December 5
9h30 - 12h30: Journal Club
16h00 CNC Seminar: Unexpected fate and function of a single glycolipid in pigmentation (G. van Meer)
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